Complementing the surgical cytoreduction treatment with intraoperative hyperthermic chemotherapy, by regulating the temperature and flow rate in the abdominal or thoracic cavity.
Hyperthermic chemotherapy can be performed in the abdominal cavity: HIPEC or in the thoracic cavity: HITHOC.
Curative treatment of peritoneal carcinosis *:
*Peritoneal carcinoma: A tumour that spreads from its primary site in the peritoneum and can invade the entire peritoneal cavity and all the organs it contains.
The peritoneum has recently been recognised as an organ in its own right. This is a very thin, solid membrane made up of two layers that can move over each other.
Two HIPEC techniques are currently used: open-abdomen (coliseum technique) or closed-abdomen.
The important points for full HIPEC treatment are to obtain a uniform temperature throughout the abdominal cavity and uniform diffusion of the peritoneal dialysate. The temperature of the bath should be at least 41 C and no more than 43 C (risk of digestive perforation above this temperature). The duration of the hyperthermic bath (30 to 90 minutes), the technique used (open-abdomen vs. closed), the temperature of the bath and the concentration of chemotherapy vary between teams.
Open HIPEC: coliseum technique
Closed HIPEC: Monitoring intra-abdominal pressure
The advantage of HIPEC is that it has a local action; only a very small amount of chemotherapy liquid passes into the bloodstream (unlike conventional chemotherapy), which avoids the usual side effects of chemotherapy. It has also been shown that this method of treatment increases the quality of disease control in the peritoneum, reduces the rate of relapse and increases the long-term survival rate of patients, without increasing the risk of morbidity.
The same procedure can be performed in the thoracic cavity.
Gamida Tech, 18 years of experience in the manufacture of medical devices.
In 2005, Gamida Tech designed its first piece of SunChip equipment, in collaboration with Dr Dominique Elias and the biomedical team at the Institut Gustave Roussy, Villejuif. The SunChip system is a medical device specially designed for intraperitoneal chemotherapy. Building on its experience, Gamida Tech launched the SunChip 2 in 2017, which combines the performance, safety and precision of the SunChip with new features in terms of design and simplicity for greater versatility.